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Selective α,δ-hydrocarboxylation of conjugated dienes utilizing CO2 and electrosynthesis
journal contribution
posted on 2020-07-21, 11:14 authored by Ahmed Sheta, Mohammad A Mashaly, Samy B Said, Saad S Elmorsy, Andrei MalkovAndrei Malkov, Benjamin BuckleyBenjamin BuckleyTo date the majority of diene carboxylation processes afford the α,δ-dicarboxylated product, the selective mono-carboxylation of dienes is a significant challenge and the major product reported under transition metal catalysis arises from carboxylation at the α-carbon. Herein we report a new electrosynthetic approach, that does not rely on a sacrificial electrode, the reported method allows unprecedented direct access to carboxylic acids derived from dienes at the δ-position. In addition, the α,δ-dicarboxylic acid or the α,δ-reduced alkene can be easily accessed by simple modification of the reaction conditions.
Funding
EPSRC (EP/P030599/1)
History
School
- Science
Department
- Chemistry
Published in
Chemical ScienceVolume
11Issue
34Pages
9109 - 9114Publisher
Royal Society of Chemistry (RSC)Version
- VoR (Version of Record)
Rights holder
© The Royal Society of ChemistryPublisher statement
This is an open access article. It is published by the Royal Society of Chemistry under the Creative Commons Attribution 3.0 Unported Licence (CC BY). Full details of this licence are available at: https://creativecommons.org/licenses/by/3.0/Acceptance date
2020-07-13Publication date
2020-07-20Copyright date
2020ISSN
2041-6520eISSN
2041-6539Publisher version
Language
- en
Depositor
Prof Andrei Malkov. Deposit date: 21 July 2020Usage metrics
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