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Sprint interval and traditional endurance training induce similar improvements in peripheral arterial stiffness and flow-mediated dilation in healthy humans

journal contribution
posted on 20.11.2014, 09:46 by Mark Rakobowchuk, Sophie Tanguay, Kirsten A. Burgomaster, Kritsa R. Howarth, Martin J. Gibala, Maureen Macdonald
Low-volume sprint interval training (SIT), or repeated sessions of brief, intense intermittent exercise, elicits metabolic adaptations that resemble traditional high-volume endurance training (ET). The effects of these different forms of exercise training on vascular structure and function remain largely unexplored. To test the hypothesis that SIT and ET would similarly improve peripheral artery distensibility and endothelial function and central artery distensibility, we recruited 20 healthy untrained subjects (age: 23.3 ± 2.8 yr) and had them perform 6 wk of SIT or ET (n = 5 men and 5 women per group). The SIT group completed four to six 30-s “all-out” Wingate tests separated by 4.5 min of recovery 3 days/wk. The ET group completed 40–60 min of cycling at 65% of their peak oxygen uptake (V̇o2peak) 5 days/wk. Popliteal endothelial function, both relative and normalized to shear stimulus, was improved after training in both groups (main effect for time, P < 0.05). Carotid artery distensibility was not statistically altered by training (P = 0.29) in either group; however, popliteal artery distensibility was improved in both groups to the same degree (main effect, P < 0.05). We conclude that SIT is a time-efficient strategy to elicit improvements in peripheral vascular structure and function that are comparable to ET. However, alterations in central artery distensibility may require a longer training stimuli and/or greater initial vascular stiffness than observed in this group of healthy subjects.

Funding

This work was supported by operating grants from the National Sciences and Engineering Research Council of Canada (NSERC; to M. J. MacDonald and M. J. Gibala). M. Rakobowchuk is the recipient of a Canadian Graduate Scholarship from the Canadian Institutes of Health Research. K. A. Burgomaster was supported by an NSERC Canada Graduate Scholarship. K. R. Howarth was supported by an Ontario Graduate Scholarship.

History

School

  • Sport, Exercise and Health Sciences

Published in

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Volume

295

Issue

1

Pages

R236 - R242 (7)

Citation

RAKOBOWCHUK, M. ... et al, 2008. Sprint interval and traditional endurance training induce similar improvements in peripheral arterial stiffness and flow-mediated dilation in healthy humans. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 295 (1), pp.R236-R242.

Publisher

© American Physiological Society

Version

NA (Not Applicable or Unknown)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2008

Notes

This paper is closed access.

ISSN

0363-6119

Language

en