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Maternal reproductive health REVISION FINAL after secon revision.pdf (423.7 kB)

Testing the Institute of Medicine (IOM) recommendations on maternal reproductive health and associated neonatal characteristics in a transitional, Mediterranean population

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posted on 2022-07-20, 14:36 authored by Jelena Šarac, Dubravka Havas-Augustin, Matea Zajc Petranović, Natalija Novokmet, Luka Bockor, Lada Stanišić, Emily PetherickEmily Petherick, Deni Karelović, Alen Šelović, Rafaela Mrdjen Hodžić, Sanja Music Milanovic, Ellen W. Demerath, Lawrence M. Schell, Noel Cameron, Sasa Missoni

Background: 

High pre-pregnancy body mass index (BMI) and excessive gestational weight gain (GWG) are significant risk factors for maternal and neonatal health. 

Aim: 

To assess pre-pregnancy BMI and GWG during pregnancy and their association with different maternal and neonatal characteristics in the transitional Mediterranean population from the Eastern Adriatic islands. 

Subjects and methods: 

Two hundred and sixty-two mother–child dyads from the CRoatian Islands’ Birth Cohort Study (CRIBS) were included in the study. Chi-square test, ANOVA, and regression analysis were used to test the association between selected characteristics. Results: In total, 22% of women entered pregnancy as overweight/obese and 46.6% had excessive GWG. Pre-pregnancy overweight and obesity were significantly associated with elevated triglycerides uric acid levels, and decreased HDL cholesterol in pregnancy. Excessive GWG was associated with elevated fibrinogen and lipoprotein A levels. Women with high pre-pregnancy BMI and GWG values were more likely to give birth to babies that were large for gestational age (LGA), additionally confirmed in the multiple logistic regression model. 

Conclusion: 

High maternal pre-pregnancy BMI and excessive GWG were both significantly associated with deviated biochemical parameters and neonatal size. More careful monitoring of maternal nutritional status can lead to better pre- and perinatal maternal healthcare.

Funding

Croatian Science Foundation, grant number HRZZ UIP-2014–09–6598

History

School

  • Sport, Exercise and Health Sciences

Published in

Annals of Human Biology

Volume

49

Issue

2

Pages

91-99

Publisher

Informa UK Limited

Version

  • AM (Accepted Manuscript)

Rights holder

© Informa UK Limited

Publisher statement

This is an Accepted Manuscript version of the following article, accepted for publication in Annals of Human Biology. Jelena Šarac, Dubravka Havaš Auguštin, Matea Zajc Petranović, Natalija Novokmet, Luka Bočkor, Lada Stanišić, Emily Petherick, Deni Karelović, Alen Šelović, Rafaela Mrdjen Hodžić, Sanja Musić Milanović, Ellen W. Demerath, Lawrence M. Schell, Noël Cameron & Saša Missoni (2022) Testing the Institute of Medicine (IOM) recommendations on maternal reproductive health and associated neonatal characteristics in a transitional, Mediterranean population, Annals of Human Biology, 49:2, 91-99, DOI: 10.1080/03014460.2022.2080863. It is deposited under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

Acceptance date

2022-05-07

Publication date

2022-06-20

Copyright date

2022

ISSN

0301-4460

eISSN

1464-5033

Language

  • en

Depositor

Dr Emily Petherick. Deposit date: 20 July 2022

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