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The effect of eight weeks of passive heat therapy on mental health, sleep, and chronic pain in persons with spinal cord injury: a pilot study

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posted on 2025-10-16, 12:25 authored by Hannah Uhlig-Reche, Sven Hoekstra, Yubo WuYubo Wu, Dean Lundt Kellogg, Jr., Terry Romo, Christof LeichtChristof Leicht, Michelle B. Trbovich
<p dir="ltr"><b>Background/Objectives</b>: Rates of depression, anxiety, sleep disturbances, and chronic pain are higher in people with spinal cord injury (SCI) compared with able-bodied individuals. Passive heat therapy (PHT), which raises core body temperature, may be an accessible therapeutic intervention. The effects of PHT on mental health, sleep, and pain in persons with SCI are unknown.</p><p dir="ltr"><b>Methods</b>: We performed a time-controlled pre–post intervention pilot study in which ten veterans with chronic SCI underwent an 8-week supervised PHT intervention to raise oral temperature by 1 °C each session. Outcome measures were the 5-item Mental Health Inventory, Epworth Sleepiness Scale, and International Spinal Cord Injury Pain Extended Data Sets version 1.0.</p><p dir="ltr"><b>Results</b>: There were no adverse events related to the intervention and nine out of ten participants completed all their intervention sessions. There was a reduction in pain intensity (p = 0.039) upon completing the intervention (from a median (IQR) of 2.0 (0.0, 3.5) to 1.0 (0.0, 4.5) on a 0–10 scale). However, there were no improvements in self-reported mental health or sleep outcomes (p > 0.339).</p><p dir="ltr"><b>Conclusions</b>: This pilot study suggests that supervised repeated passive heat therapy may confer benefits for chronic pain in veterans with chronic SCI. Follow-up studies with larger sample sizes and more extensive sets of chronic pain outcomes are needed to confirm these findings.</p>

Funding

VA Rehabilitation R&D (I21RX003724-01A1)

History

School

  • Sport, Exercise and Health Sciences

Published in

Journal of Clinical Medicine

Volume

14

Issue

10

Article number

3566

Publisher

MDPI AG

Version

  • VoR (Version of Record)

Rights holder

© The Author(s)

Publisher statement

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Acceptance date

2025-05-17

Publication date

2025-05-20

Copyright date

2025

eISSN

2077-0383

Language

  • en

Depositor

Dr Christof Leicht. Deposit date: 16 October 2025

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