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The first enantiomerically pure thiadiazol-3-one 1-oxide and thiatriaza-indene 3-oxide systems chiral at the sulfur atom
journal contribution
posted on 2014-01-14, 15:27 authored by Benjamin BuckleyBenjamin Buckley, Stephen P. Neary, Mark ElsegoodMark ElsegoodThe first synthesis of an enantiomerically pure C2 symmetric benzothiadiazole 2-oxide is described along with the first synthesis of an enantiomerically thiadiazol-3-one 1-oxide and a thiatriaza-indene 3-oxide system both chiral at the sulfur atom. Excellent levels of diastereoselectivity were observed in the SO installation step, that is, the reaction of the prerequisite bis-amines with thionyl chloride at ambient temperature.
History
School
- Science
Department
- Chemistry
Citation
BUCKLEY, B.R., NEARY, S.P. and ELSEGOOD, M.R.J., 2010. The first enantiomerically pure thiadiazol-3-one 1-oxide and thiatriaza-indene 3-oxide systems chiral at the sulfur atom. Tetrahedron: Asymmetry, 21 (16), pp. 1959 - 1962Publisher
© ElsevierVersion
- AM (Accepted Manuscript)
Publication date
2010Notes
This article was published in the journal Tetrahedron: Asymmetry [© Elsevier]. The definitive version is available at: http://dx.doi.org/10.1016/j.tetasy.2010.07.025ISSN
0957-4166Publisher version
Language
- en