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The first enantiomerically pure thiadiazol-3-one 1-oxide and thiatriaza-indene 3-oxide systems chiral at the sulfur atom

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journal contribution
posted on 14.01.2014, 15:27 by Benjamin Buckley, Stephen P. Neary, Mark Elsegood
The first synthesis of an enantiomerically pure C2 symmetric benzothiadiazole 2-oxide is described along with the first synthesis of an enantiomerically thiadiazol-3-one 1-oxide and a thiatriaza-indene 3-oxide system both chiral at the sulfur atom. Excellent levels of diastereoselectivity were observed in the SO installation step, that is, the reaction of the prerequisite bis-amines with thionyl chloride at ambient temperature.

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  • Science

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  • Chemistry

Citation

BUCKLEY, B.R., NEARY, S.P. and ELSEGOOD, M.R.J., 2010. The first enantiomerically pure thiadiazol-3-one 1-oxide and thiatriaza-indene 3-oxide systems chiral at the sulfur atom. Tetrahedron: Asymmetry, 21 (16), pp. 1959 - 1962

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© Elsevier

Version

AM (Accepted Manuscript)

Publication date

2010

Notes

This article was published in the journal Tetrahedron: Asymmetry [© Elsevier]. The definitive version is available at: http://dx.doi.org/10.1016/j.tetasy.2010.07.025

ISSN

0957-4166

Language

en

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