Theory of pore-driven and end-pulled polymer translocation dynamics through a nanopore: an overview
journal contributionposted on 04.10.2018, 13:19 by Jalal Sarabadani, Tapio Ala-NissilaTapio Ala-Nissila
© 2018 IOP Publishing Ltd. We review recent progress on the theory of dynamics of polymer translocation through a nanopore based on the iso-flux tension propagation (IFTP) theory. We investigate both pore-driven translocation of flexible and a semi-flexible polymers, and the end-pulled case of flexible chains by means of the IFTP theory and extensive molecular dynamics (MD) simulations. The validity of the IFTP theory can be quantified by the waiting time distributions of the monomers which reveal the details of the dynamics of the translocation process. The IFTP theory allows a parameter-free description of the translocation process and can be used to derive exact analytic scaling forms in the appropriate limits, including the influence due to the pore friction that appears as a finite-size correction to asymptotic scaling. We show that in the case of pore-driven semi-flexible and end-pulled polymer chains the IFTP theory must be augmented with an explicit trans side friction term for a quantitative description of the translocation process.
This work was supported in part by the Academy of Finland through its Centers of Excellence program under project Nos. 251748, 284621 and 312298.
- Mathematical Sciences