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Time course of regional vascular adaptations to low load resistance training with blood flow restriction

journal contribution
posted on 23.06.2014, 13:45 by Julie E.A. Hunt, Dermot Galea, Graham Tufft, Danny Bunce, Richard FergusonRichard Ferguson
Distortion to hemodynamic and ischemic stimuli during blood flow restriction (BFR) exercise may influence regional vascular adaptation. We examined changes at the conduit, resistance, and capillary level in response to low load resistance exercise with BFR. Eleven males (22 ± 3 yr, 178 ± 4 cm, 78 ± 9 kg) completed 6 wk (3 days/wk) unilateral plantar flexion training with BFR at 30% 1 repetition maximum (1-RM). The contralateral leg acted as a nonexercised control (CON). Popliteal artery function [flow-mediated dilation, FMD%] and structure [maximal diameter] and resistance vessel structure [peak reactive hyperemia] were assessed using Doppler ultrasound before and at 2-wk intervals. Calf filtration capacity was assessed using venous occlusion plethysmography before and after training. BFR training elicited an early increase in peak reactive hyperemia (1,400 ± 278 vs. 1,716 ± 362 ml/min at 0 vs. 2 wk; t-test: P = 0.047), a transient improvement in popliteal FMD% (5.0 ± 2.1, 7.6 ± 2.9, 6.6 ± 2.1, 5.7 ± 1.6% at 0, 2, 4 and 6 wk, respectively; ANOVA: P = 0.002), and an increase in maximum diameter (6.06 ± 0.44 vs. 6.26 ± 0.39 mm at 0 vs. 6 wk; Bonferroni t-test: P = 0.048). Capillary filtration increased after 6 wk BFR training (P ± 0.043). No changes in the CON leg were observed. Adaptation occurred at all levels of the vascular tree in response to low load resistance exercise with BFR. Enhanced peak reactive hyperemia and transient improvement in popliteal artery function occurred before changes in artery structural capacity. Copyright © 2013 the American Physiological Society.

History

School

  • Sport, Exercise and Health Sciences

Published in

Journal of Applied Physiology

Volume

115

Issue

3

Pages

403 - 411

Citation

HUNT, J.E.A. ... et al, 2013. Time course of regional vascular adaptations to low load resistance training with blood flow restriction. Journal of Applied Physiology, 115 (3), pp. 403 - 411

Publisher

© American Physiological Society

Version

AM (Accepted Manuscript)

Publication date

2013

Notes

This article is closed access.

ISSN

8750-7587

eISSN

1522-1601

Language

en

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Keywords

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