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Transmembrane transport of fluoride studied by time-resolved emission spectroscopy

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journal contribution
posted on 2023-09-29, 15:21 authored by Alessio Cataldo, Matúš Chvojka, Gyeongjin Park, Vladimír Šindelář, François P Gabbaï, Stephen ButlerStephen Butler, Hennie Valkenier

Here we present a new method to monitor fluoride transmembrane transport into liposomes using a europium(III) complex. We take advantage of the long emission lifetime of this probe to measure the transport activity of a fluorescent transporter. The high sensitivity, selectivity, and versatility of the assay allowed us to study different types of fluoride transporters and unravel their mechanisms of action.

Funding

Transport of phosphorylated compounds across lipid bilayers by supramolecular receptors

European Research Council

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Luminescent Host Molecules for Multisite Recognition of Polyphosphate Anions

Engineering and Physical Sciences Research Council

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National Science Foundation (CHE-2108728)

Welch Foundation (A-1423)

Czech Science Foundation (No. GA20- 13922S)

History

School

  • Science

Department

  • Chemistry

Published in

Chemical Communications

Volume

59

Issue

28

Pages

4185 - 4188

Publisher

Royal Society of Chemistry

Version

  • VoR (Version of Record)

Rights holder

© The Authors

Publisher statement

This is an Open Access Article. It is published by the Royal Society of Chemistry under the Creative Commons Attribution 3.0 Unported Licence (CC BY). Full details of this licence are available at: https://creativecommons.org/licenses/by/3.0/

Acceptance date

2023-03-13

Publication date

2023-03-14

Copyright date

2023

ISSN

1359-7345

eISSN

1364-548X

Language

  • en

Depositor

Deposit date: 29 September 2023

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