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URI in athletes: are mucosal immunity and cytokine responses key risk factors?
journal contributionposted on 23.02.2015, 16:24 authored by Michael Gleeson, Nicolette BishopNicolette Bishop
Infection incidence among athletes is highest during periods of intensified training and competition and after strenuous long-distance events. Which aspects of depressed immune function are responsible for this increased infection risk are not known, but our hypothesis is that lower salivary immunoglobulin A (IgA) secretion and a higher antiinflammatory cytokine response to antigen exposure are key determinants of infection risk.
This work was supported by GlaxoSmithKline, UK, and Yakult Honsha, Japan.
- Sport, Exercise and Health Sciences