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URI in athletes: are mucosal immunity and cytokine responses key risk factors?

journal contribution
posted on 23.02.2015, 16:24 authored by Michael Gleeson, Nicolette BishopNicolette Bishop
Infection incidence among athletes is highest during periods of intensified training and competition and after strenuous long-distance events. Which aspects of depressed immune function are responsible for this increased infection risk are not known, but our hypothesis is that lower salivary immunoglobulin A (IgA) secretion and a higher antiinflammatory cytokine response to antigen exposure are key determinants of infection risk.

Funding

This work was supported by GlaxoSmithKline, UK, and Yakult Honsha, Japan.

History

School

  • Sport, Exercise and Health Sciences

Published in

EXERCISE AND SPORT SCIENCES REVIEWS

Volume

41

Issue

3

Pages

148 - 153 (6)

Citation

GLEESON, M. and BISHOP, N., 2013. URI in athletes: are mucosal immunity and cytokine responses key risk factors? Exercise and Sport Sciences Reviews, 41 (3), pp. 148 - 153.

Publisher

Lippincott, Williams & Wilkins / © American College of Sports Medicine

Version

VoR (Version of Record)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2013

Notes

This article is closed access.

ISSN

0091-6331

Language

en