Very bright europium complexes that stain cellular mitochondria

Walton, James W.; Bourdolle, Adrien; Butler, Stephen; Soulie, Marine; Delbianco, Martina; McMahon, Brian K.; Pal, Robert; Puschmann, Horst; Zwier, Jurriaan M.; Lamarque, Laurent; Maury, Olivier; Andraud, Chantal; Parker, David

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Very bright europium complexes that stain cellular mitochondria

journal contribution

posted on 2015-09-15, 14:54 authored by James W. Walton, Adrien Bourdolle, Stephen ButlerStephen Butler, Marine Soulie, Martina Delbianco, Brian K. McMahon, Robert Pal, Horst Puschmann, Jurriaan M. Zwier, Laurent Lamarque, Olivier Maury, Chantal Andraud, David Parker

The synthesis, structure and photophysical properties of a series of highly emissive europium complexes is reported. Certain complexes enter mammalian cells by macropinocytosis and stain the mitochondria selectively, allowing observation of the Eu emission in cellulo by time-gated spectral imaging

Funding

We thank the EPSRC, ESF COST CM-1006 and the ERC (DP) for support (FCC 266804).

History

School

Science

Department

Chemistry

Published in

CHEMICAL COMMUNICATIONS

Volume

49

Issue

16

Pages

1600 - 1602 (3)

Citation

WALTON, J.W. ... et al, 2013. Very bright europium complexes that stain cellular mitochondria. Chemical Communications, 49 (16), pp. 1600 - 1602.

Publisher

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2013

Notes

This article was accepted for publication in the journal, Chemical Communications [© Royal Society of Chemistry]. The definitive version is available at: http://dx.doi.org/10.1039/c2cc35247h