A study of the application of imaging charge-coupled devices for the detection and quantitation of luminogenic assays

Low light level imaging devices have the advantage that they can produce quantitative two dimensional images. The characteristics, structure and operation of different low light level imaging devices are discussed. Cooled slow scanned charged coupled device (CCD) cameras show good detector properties; very low dark noise; low system noise; good spatial resolution; therefore seem ideal for the detection and quantitation of luminogenic assays. [Continues.]