Analytical applications of thin-layer phosphorimetry
thesisposted on 2018-11-19, 15:15 authored by Aliei Ismaiel-Al-Mosawi
The aim of the present work was to eliminate some of the problems associated with phosphorimetric techniques. Also to extend the use or the application of phosphorescence as an analytical tool to a number of different classes of drugs and determining them in low concentrations. The aim was to extend the application to environmental pollution by studying the characteristics of thirteen polycyclic aromatic hydrocarbons in solutions and on thin layer phosphorimetry. When this work started thin-layer phosphorimetry was already developed, the aim of this work is to examine the usefulness of TLC phosphorimetry for different groups of drugs and related compounds which have not been studied previously by this technique, and to determine them in very low concentrations. The sensitivity of phosphorescence and thin-layer chromatography could be combined to produce a rapid, sensitive and selective method of analysis capable of resolving small quantities of similar compounds, especially drugs and their metabolites, from complex mixtures.
Publisher© Aliei Ismaiel-Al-Mosawi
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NotesA Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of the degree of Doctor of Philosophy at Loughborough University.