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Aspects of steroidal partial synthesis and rearrangements

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posted on 2017-08-24, 13:36 authored by Rafael T. Silva
The previously reported conversion of 3ß-tosyloxy-5α-cholestane-5, 6ß-diol with Buᵗ0K/Buᵗ0H to 3ß-methyl-A-nor-5ß-cholestan-5-ol-6-one, is believed to arise from a novel intramolecular ene reaction of an intermediate unsaturated acyloin, 4,5-seco-cholest-3-en-6ß-ol-5-one. It was proposed to synthesise the unsaturated acyloin 4,5-secocholest- 3-en-6ß-ol-5-one to determine whether it would indeed undergo the ene reaction. [continues…]

Funding

National Council of Research and Technology (CONACYT), Mexico.

History

School

  • Science

Department

  • Chemistry

Publisher

© Rafael T. Silva

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

1982

Notes

A Masters Thesis. Submitted in partial fulfilment of the requirements for the award of Master of Philosophy of Loughborough University.

Language

  • en

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    Chemistry Theses

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    Keywords

    untaggedChemical Sciences not elsewhere classified

    Licence

    CC BY-NC-ND 4.0

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