Thesis-1992-Karekezi.pdf (4.17 MB)
Download fileAspects of the biological activity of the schistosomicide oxamniquine
thesis
posted on 2017-12-18, 09:51 authored by Catherine W. KarekeziOxamniquine, 6-hydroxymethyl-2-N-isopropylaminomethyl-7-nitro-1,2,3,4-
tetrahydroquinoline, is a potent schistosomicide used clinically in the treatment of
infections due to Schistosoma mansoni. Schistosomiasis is the second most
important tropical disease after malaria. Although oxamniquine is relatively well
tolerated, severe central nervous system (CNS) effects characterized by
convulsions, have been reported in a small percentage of the population treated
with this drug. [Continues.]
Funding
Association of Commonwealth Universities, Commonwealth Scholarship Commission.
History
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- Science
Department
- Chemistry