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Bio-analytical studies of the bleomycins

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thesis
posted on 18.10.2018, 11:04 authored by Clive R. Williams
The plasma concentrations and urine levels of bleomycin in patients undergoing bleomycin therapy are of considerable interest since they may give an indication of the amount of bleomycin left in the body and hence that amount which is potentially available to the tumour. These levels are also important since bleomycin shave toxic effects and the onset of toxic effects in patients is quite variable. … In view of the variable excretion and the differing tumour : blood ratios of the various bleomycins, there is a need not only to determine total bleomycin levels but also the individual bleomycins.

History

School

  • Science

Department

  • Chemistry

Publisher

© Clive Rowland Williams

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

1978

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.

Language

en

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