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Development of a scalable upstream bioprocess for bacteriophage culture

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posted on 2020-05-29, 07:50 authored by Junaid Ali
Since the discovery of antibiotics, there has been a revolution in treating microbial infections. However, with their increasing use, some microbes have developed a form of resistance to many of the available antimicrobial agents. Untreatable infections because of antimicrobial resistance (AMR) have recently become a global threat and it is estimated that by 2050, more than 10 million people will die per annum from resistant bacterial infections. Therefore, novel methods are needed to kill resistant microbes. One such method that may be used to kill resistant bacteria are bacteriophages (phages), viruses that infect microorganisms and cause them to lyse. [Continues.]

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Publisher

Loughborough University

Rights holder

© Junaid Anees Ali

Publication date

2020

Notes

A doctoral thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy of Loughborough University.

Language

  • en

Supervisor(s)

Elizabeth Ratcliffe ; Qasim Rafiq

Qualification name

  • PhD

Qualification level

  • Doctoral

This submission includes a signed certificate in addition to the thesis file(s)

  • I have submitted a signed certificate

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