Thesis-1979-Fayad.pdf (3.99 MB)
Download fileDifferential pulse polarographic study of drug compounds
thesis
posted on 10.01.2018, 11:22 authored by Nabil M.M. FayadThe work discussed in this thesis is in three parts. The
initial work carried out was to develop a differential pulse
polarographic (DPP) method for the determination of disodium
cromoglycate (INTAL) in human urine samples. The method eventually
recommended involves an ion-pair extraction of the cromoglycate
with tri-n-butylbenzylphosphonium chloride into chloroform. After
evaporating the chloroform and dissolving the residue in a buffer
solution, down to 0.5 μg INTAL per ml urine can be determined.
The method has the distinct advantages of simplicity and speed
over the colorimetric method currently in use. [Continues.]
History
School
- Science
Department
- Chemistry