Thesis-1973-Gifford.pdf (2.8 MB)
Low-temperature luminescence analysis of drugs and poisons
thesisposted on 2018-11-02, 12:03 authored by Lawrence A. Gifford
It is the aim of this work to extend the use of phosphorescence as an analytical technique to a number of different classes of drugs and to study any structure–spectral correlations existing between them. Part of the present work is directed towards developing a technique capable of scanning thin-layer chromatograms and measuring the phosphorescence of separated components in situ. The sensitivity of phosphorescence and separatory function of thin-layer chromatography could thus be combined to produce a rapid, sensitive method capable of resolving small quantities of similar compounds, especially drugs and their metabolites, from complex mixtures.
Medical Research Council.
Publisher© Lawrence Albert Gifford
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NotesA Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of the degree of Doctor of Philosophy at Loughborough University.