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Low-temperature luminescence analysis of drugs and poisons

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thesis
posted on 02.11.2018, 12:03 authored by Lawrence A. Gifford
It is the aim of this work to extend the use of phosphorescence as an analytical technique to a number of different classes of drugs and to study any structure–spectral correlations existing between them. Part of the present work is directed towards developing a technique capable of scanning thin-layer chromatograms and measuring the phosphorescence of separated components in situ. The sensitivity of phosphorescence and separatory function of thin-layer chromatography could thus be combined to produce a rapid, sensitive method capable of resolving small quantities of similar compounds, especially drugs and their metabolites, from complex mixtures.

Funding

Medical Research Council.

History

School

  • Science

Department

  • Chemistry

Publisher

© Lawrence Albert Gifford

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

1973

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of the degree of Doctor of Philosophy at Loughborough University.

Language

en

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