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New aromatic dialdehyde labels for analytical fluorimetry

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thesis
posted on 23.11.2017 by Mohammad Aminuddin
Fluorigenic aromatic molecules have found wide application in Fluorescence Spectroscopy. Commercially available fluorigenic reagents have been used to detect amines, amino acids, peptides and proteins. Orthophthalaldehyde (OPA) is an aromatic dialdehyde which is specific for a primary amino group. Three polyaromatic dialdehyde molecules similar to this compound have been synthesised and investigated for their analytical applications. They are: (1) naphthalene-2,3- dicarboxaldehyde (NDA), (2) 1-phenylnaphthalene-2, 3- dicarboxaldehyde (0NDA) and (3) anthracene-2,3- dicarboxaldehyde (ADA). [Continues.]

Funding

British Council.

History

School

  • Science

Department

  • Chemistry

Publisher

© M. Aminuddin

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 2.5 Generic (CC BY-NC-ND 2.5) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/2.5/

Publication date

1987

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.

Language

en

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