Thesis-1982-Martin.pdf (5.36 MB)

Polarographic studies of beta-lactam degradations

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thesis
posted on 09.12.2013 by Michael Joseph Martin
Alkaline degradation studies were followed polarographically for eleven cephalosporins. Correlations are apparent in that most compounds give waves at -0.J9 V (pH 2) and -0.50 V (pH 2); these are the initial and secondary polarographically active alkaline degradation products respectively. Possible structures for these degradation products are suggested which contain a reducible carbon-nitrogen double bond in the 6-membered thiazine ring analogous to 1,4-benzodiazepines [continued]...

History

School

  • Science

Department

  • Chemistry

Publisher

© Michael Joseph Martin

Publication date

1982

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy of Loughborough University.

Language

en

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