Thesis-1985-Joshi.pdf (3.45 MB)
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Some studies with quinazolines and related compounds

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thesis
posted on 19.02.2018, 17:11 authored by Bijaya L. Joshi
The thesis reports a study of new methods of modification of the medicinally important quinazoline system by the use of Reissert compounds. Previous attempts to employ this approach have utilized two phase conditions leading only to ring opened products. We have discovered that reaction of 4-phenylquinazoline with an acid chloride and trimethylsilyl cyanide as source of cyanide ion in a single phase system selectively gives a high yield route to the corresponding 1-acyl-2-cyano-1,2-dihydroquinazoline. [Continues.]

Funding

British Council.

History

School

  • Science

Department

  • Chemistry

Publisher

© Bijaya Luxmi Joshi

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 2.5 Generic (CC BY-NC-ND 2.5) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/2.5/

Publication date

1985

Notes

A master's thesis submitted in partial fulfilment of the requirements for the award of Master of Philosophy at Loughborough University.

Language

en

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