Thesis-1985-Joshi.pdf (3.45 MB)
Download fileSome studies with quinazolines and related compounds
thesis
posted on 2018-02-19, 17:11 authored by Bijaya L. JoshiThe thesis reports a study of new methods of modification of the
medicinally important quinazoline system by the use of Reissert compounds.
Previous attempts to employ this approach have utilized two phase conditions
leading only to ring opened products. We have discovered that reaction of
4-phenylquinazoline with an acid chloride and trimethylsilyl cyanide as
source of cyanide ion in a single phase system selectively gives a high
yield route to the corresponding 1-acyl-2-cyano-1,2-dihydroquinazoline. [Continues.]
Funding
British Council.
History
School
- Science
Department
- Chemistry
Publisher
© Bijaya Luxmi JoshiPublisher statement
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 2.5 Generic (CC BY-NC-ND 2.5) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/2.5/Publication date
1985Notes
A master's thesis submitted in partial fulfilment of the requirements for the award of Master of Philosophy at Loughborough University.Language
- en