posted on 2017-12-15, 14:13authored byAngela S. Mallard
This report describes studies concerning bridged isoquinolines and
related compounds, Four aspects have been studied,
Firstly, Diels-Alder reactions between heterarynes and different dienes
have been carried out to provide 5,8-bridged isoquinolines. The reaction
between 2,5,6-trichloro-3,4-pyridyne and p-diisopropyl benzene thus led to
1,3,4-trichloro-5,8-dihydro-6,9-diisopropyl-5,8-ethenoisoquinoline but
only in 18% yield. Studies involving other heterarynes in Diels-Alder
processes have been made. [Continues.]
Funding
Science Research Council and Reckitt and Colman PLC, Pharmaceutical Division (CASE research studentship).
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 2.5 Generic (CC BY-NC-ND 2.5) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-nd/2.5/
Publication date
1982
Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.