Thesis-1971-Chhabra.pdf (4.85 MB)
Download file

Studies concerning partially reduced nitrogen heterocycles

Download (4.85 MB)
thesis
posted on 30.10.2018, 17:15 by Siri R. Chhabra
Carbanion rearrangement studies on selected N-acyl-isoquinoline and -quinoline Reissert compounds have shown that alternative intramolecular rearrangements can compete successfully with the normal 1,2-acyl-migration. The observations have been rationalised mechanistically and their potential value in synthesis demonstrated. In particular the formation of a 1-benzoyl-8-hydroxyisoquinoline derivative has been effected from carbanion rearrangement of the corresponding 8-benzoyloxy Reissert compound. N-Crotonoylisoquinoline Reissert compound carbanion and analogous structures have been shown to undergo a complex reaction in which Michael type attack competes with the normal migration. [Continues.]

Funding

Loughborough University of Technology.

History

School

  • Science

Department

  • Chemistry

Publisher

© Siri Ram Chhabra

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

1971

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.

Language

en

Usage metrics

Keywords

Exports