Tandem reactions of oxiranylcarbinyl radicals
thesisposted on 27.10.2017, 08:51 by John A. Rudderham
The work described in this thesis is an investigation into the reactivity and possible synthetic applications of oxiranylcarbinyl radicals. These radicals rapidly rearrange via β-cleavage, which can proceed by breakage of either the C-O or the C-C bond. Cleavage of the latter only occurs when the molecule has a vinyl or phenyl stabilising group attached to the epoxide ring. [Continues.]
EPSRC. SmithKline Beecham Pharmaceuticals.