posted on 2018-05-24, 10:15authored byGambo L. Abdullahi
A study of the luminescence properties of alpha-1-acid glycoprotein
(α1AAGP) and its basic drug binding properties was carried out.
The fluorescence and phosphorescence properties of the protein were
studied. The luminescence were found not to differ from those of a typical
protein.
The effect of basic drug binding on the α1AAGP fluorescence or
the drug fluorescence quantum yield was investigated. Drugs studied were;
propranolol, chlorpromazine and imipramine. Only chlorpromazine showed
quenching of the protein fluorescence. [Continues.]
Funding
Nigeria, Government. University of Maiduguri (Nigeria).
This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/
Publication date
1984
Notes
A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.