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The luminescence studies of alpha-1-acid glycoprotein and its basic drug-binding properties

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posted on 24.05.2018, 10:15 by Gambo L. Abdullahi
A study of the luminescence properties of alpha-1-acid glycoprotein (α1AAGP) and its basic drug binding properties was carried out. The fluorescence and phosphorescence properties of the protein were studied. The luminescence were found not to differ from those of a typical protein. The effect of basic drug binding on the α1AAGP fluorescence or the drug fluorescence quantum yield was investigated. Drugs studied were; propranolol, chlorpromazine and imipramine. Only chlorpromazine showed quenching of the protein fluorescence. [Continues.]

Funding

Nigeria, Government. University of Maiduguri (Nigeria).

History

School

  • Science

Department

  • Chemistry

Publisher

© G.L. Abdullahi

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

1984

Notes

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.

Language

en

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Keywords

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